December 17, 2025

Protect Your Family and Customers from Rodent-Borne Diseases

The Black Death probably isn’t something that comes up in everyday conversation, but it’s worth remembering that one of the deadliest pandemics in history was linked to rats. Fleas feeding on infected rodents transmitted the bubonic plague to humans, with devastating results.

More than 700 years later, bubonic plague is extremely rare and treatable, but it hasn’t disappeared entirely. More importantly, it serves as a reminder that rodent-borne diseases persist today. Rats and mice can spread illness through their droppings, urine, bites, and the parasites they carry, especially when they move indoors during cooler weather.

For homeowners and business owners alike, rodent control and prevention isn’t just about avoiding damage or nuisance activity. It’s about protecting the people inside your home or building.

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What This Blog Covers

In this article, you’ll learn:

Rodent-Borne Diseases in Texas and Oklahoma

Salmonella and E. coli

If you’ve ever had food poisoning, you know how miserable it can be. Rodents can contaminate food, food prep surfaces, and water sources with bacteria like salmonella and E. coli, leading to symptoms such as diarrhea, abdominal pain, and fever.

While many people recover with rest and fluids, severe cases can require medical care, particularly for children, older adults, or individuals with compromised immune systems. Homes, restaurants, warehouses, and other commercial facilities are especially vulnerable when rodents gain access to food storage or preparation areas.

Hantavirus

Hantavirus is one of the more serious rodent-borne illnesses. People can become infected by inhaling airborne particles from rodent droppings, urine, or disturbed nesting materials—often during cleaning or renovation projects.

Early symptoms can be flu-like, making it easy to dismiss them at first. However, hantavirus can become severe quickly, making safe cleanup practices and professional rodent control extremely important.

Leptospirosis

Leptospirosis is a bacterial disease that spreads through water or surfaces contaminated with rodent urine. While rare, it can cause serious complications such as kidney or liver damage if not treated promptly.

People who work outdoors, manage properties, or handle animals may face higher exposure risks, making rodent prevention especially important for farms, warehouses, and commercial properties.

Rat Bite Fever

As the name suggests, rat bite fever is spread through rodent bites or scratches, or through contact with contaminated surfaces. Early symptoms often resemble the flu, but untreated cases can lead to joint swelling, skin rashes, and more serious conditions like heart or nervous system infections.

Prompt medical care is key, but preventing rodent activity in the first place is the best defense.

How to Avoid Rodent-Borne Diseases

The most effective way to prevent rodent-borne diseases is simple: keep mice and rats out of your home or business. That takes a combination of good sanitation, property maintenance, and professional guidance.

At The Pied Piper, we’ve helped protect homes and commercial properties from rodents for years. Here are some proven rodent prevention tips we recommend:

Make Your Yard Less Inviting

Seal Up Entry Points

Keep the Interior Unwelcoming

What to Do If Rodents Get Into Your Home or Business

Once rodents are inside, DIY solutions often fall short. Mouse traps and other store-bought products may catch a few rodents, but they rarely address the full infestation or the entry points that allowed rodents to enter in the first place. That leaves you dealing with an ongoing problem and continued health risks.

Professional rodent control is the most effective solution.

The Pied Piper offers comprehensive rodent control services designed to eliminate infestations and prevent future problems completely. We offer customized solutions for both home pest control and commercial pest control, helping protect families, employees, and customers alike.

If you’ve noticed signs of rodents or want to stay ahead of the problem, contact your nearest The Pied Piper branch today. We’re here to help keep your property rodent-free.

This blog was originally published on November 10, 2017, and has been updated to reflect the most current information. 

What The Pied Piper Customers Are Saying

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We love Pied Piper! They are the first pest control service that we have used that does things neatly without spraying all over our belongings. They are very detailed, quick to respond when we have needed them, and keep our lake property pest free so we can enjoy it fully! They also have a very friendly and helpful staff. Thanks guys! We will continue to be regular customers!

Stephanie H.

Eufaula, OK

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When the weather turned cold, we had hundreds of wasps try to enter our home to find warmth. Despite it being afternoon on a Friday with no appointment, Pied Piper came out when I called and handled the wasp problem. Gene Pearson was great. He went above and beyond. Highly recommend!

Derek S.

Eufaula, OK

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Always prompt to respond and very helpful when pest problems arise! They even came same day to set traps when I had a mouse and returned to remove the mouse after it was caught. Very pleased!

Hannah G.

Eufaula, OK

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